Organ transplantation can save or improve the lives of patients with
organ failures. Transplantation involves surgically replacing the
diseased or failed organ of a transplant recipient with a healthy organ
from a donor. In order to prevent rejection of implanted organs, most
recipients must begin a life-long regimen of immunosuppressive therapy
immediately upon receiving a donated organ. This immunosuppressive
regimen usually requires daily therapy in order to prevent organ
rejection and graft loss. Products that supplement immunosuppression
can reduce the frequency and severity of rejection and infection
episodes. These products can potentially enhance patient outcomes,
while providing potential cost savings in the treatment of
transplantation and its associated side effects.